Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368460 | 0.81 | DRD3 (0.50) | DRD2DRD3DRD4 | |
| SCHEMBL9874332 | 0.75 | DRD2 (0.61) | SIGMAR1DRD2DRD3DRD4 | |
| SCHEMBL9368439 | 0.75 | DRD2 (0.54) | DRD2DRD3DRD4 | |
| SCHEMBL7783723 | 0.75 | DRD2 (0.76) | DRD2DRD3DRD4 | |
| SCHEMBL9374318 | 0.75 | DRD2 (0.76) | SIGMAR1DRD2DRD3DRD4 | |
| SCHEMBL9378868 | 0.75 | DRD2 (0.76) | DRD2DRD3DRD4 | |
| SCHEMBL9196972 | 0.74 | DRD2 (0.53) | SIGMAR1DRD2DRD3DRD4 | |
| SCHEMBL9196981 | 0.74 | DRD2 (0.53) | SIGMAR1DRD2DRD3DRD4 | |
| SCHEMBL9196980 | 0.74 | DRD2 (0.53) | SIGMAR1DRD2DRD3DRD4 | |
| Hydrochloric Acid SCHEMBL7783718 | 0.74 | DRD2 (0.74) | SIGMAR1DRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431579-B1 | Substituted cyclohexenes as central nervous system agents | WARNER LAMBERT CO (US) | 1994-07-27 | — | — | EP | claimed |
| EP-0431579-A2 | Substituted cyclohexenes as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1991-06-12 | — | — | EP | claimed |
| EP-0431579-B1 | Substituted cyclohexenes as central nervous system agents | WARNER LAMBERT CO (US) | 1994-07-27 | — | — | EP | disclosed |
| EP-0431579-A2 | Substituted cyclohexenes as central nervous system agents | WARNER-LAMBERT COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |
| US-4975445-A | Antidepressants | WARNER-LAMBERT COMPANY (US) | 1990-12-04 | — | — | US | disclosed |