Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367291 | 1.00 | TSHR (0.47) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL11852735 | 0.82 | TSHR (0.45) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL28413175 | 0.82 | TSHR (0.45) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL11852741 | 0.82 | TSHR (0.45) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL7154074 | 0.80 | HCAR2 (0.43) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL8920771 | 0.80 | TSHR (0.43) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL7154072 | 0.80 | HCAR2 (0.43) | TSHRTP53EGLN1EGLN3HCAR2 | |
| SCHEMBL8920758 | 0.80 | TSHR (0.43) | TSHRTP53EGLN1EGLN3HCAR2 | |
| Bicarbonate SCHEMBL11121484 | 0.79 | FFAR3 (0.38) | TSHRHCAR2FFAR3TDP1ALDH1A1 | |
| Fumaric Acid SCHEMBL10381001 | 0.77 | FFAR3 (0.67) | TSHRTP53EGLN1EGLN3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11421223-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
| EP-3027754-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | enEvolv, Inc. (US) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015017866-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. (US) | 2015-02-05 | — | — | WO | disclosed |
| EP-0483674-B1 | A process for producing an aliphatic amide and salts thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5254733-A | Reacting 2-ethylcrotonaldehyde with willig reagent, then dinitrogen trioxide | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-19 | — | — | US | disclosed |
| EP-0483674-A1 | A process for producing an aliphatic amide and salts thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-05-06 | — | — | EP | disclosed |
| US-4863926-A | ANTICOAGULANTS, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| US-4782088-A | HYPOTENSIVE, ANTITHROMBOTIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| US-4778804-A | ANTICOAGULANTS, HYPOTENSIVE AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-10-18 | — | — | US | disclosed |
| US-4767768-A | ANTITHROMBIC, HYPOTENSIVE; OXIME-SUBSTITUTED | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-30 | — | — | US | disclosed |
| EP-0113106-B1 | NEW NITRO ALIPHATIC COMPOUNDS, PROCESS FOR PREPARATION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0113106-A1 | New nitro aliphatic compounds, process for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-11 | — | — | EP | disclosed |