⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961075 | 0.90 | — | — | |
| SCHEMBL6959532 | 0.88 | AGTR1 (0.47) | — | |
| SCHEMBL6959772 | 0.88 | AGTR1 (0.55) | — | |
| SCHEMBL9424195 | 0.87 | — | — | |
| SCHEMBL9490011 | 0.79 | — | — | |
| SCHEMBL6960386 | 0.77 | AGTR1 (0.59) | — | |
| SCHEMBL8954129 | 0.76 | — | — | |
| SCHEMBL8954087 | 0.76 | — | — | |
| SCHEMBL9595158 | 0.76 | — | — | |
| SCHEMBL9490000 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425211-B1 | Substituted 5-((tetrazolyl)alkenyl)-imidazoles | SMITHKLINE BEECHAM CORP (US) | 1994-03-30 | — | — | EP | disclosed |
| EP-0425211-A1 | Substituted 5-((tetrazolyl)alkenyl)-imidazoles | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-02 | — | — | EP | disclosed |