Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 3/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128596 | 1.00 | CA12 (0.37) | CA12CA1CA9MAPTKDM5A | |
| SCHEMBL21065731 | 0.97 | CA12 (0.36) | CA12CA1CA9MAPTKDM5A | |
| SCHEMBL3373345 | 0.95 | CA12 (0.34) | CA12CA1CA9MAPTKDM5A | |
| SCHEMBL3480688 | 0.92 | DNM1 (0.43) | CA12CA1CA9KDM5ADNM1 | |
| SCHEMBL1666490 | 0.89 | DNM1 (0.48) | CA12CA1CA9KDM5ADNM1 | |
| SCHEMBL9368862 | 0.89 | DNM1 (0.48) | CA12CA1CA9KDM5ADNM1 | |
| SCHEMBL3371284 | 0.89 | KCNH2 (0.40) | CA12CA1CA9MAPTKDM5A | |
| SCHEMBL21065766 | 0.89 | DNM1 (0.42) | CA12CA1CA9KDM5ADNM1 | |
| SCHEMBL4255495 | 0.89 | CA12 (0.34) | CA12CA1CA9MAPTDNM1 | |
| SCHEMBL5981812 | 0.89 | DNM1 (0.48) | CA12CA1CA9KDM5ADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319480-B1 | Process for the methylation of triazine compounds containing 2,2,6,6-tetramethylpiperidine groups | CIBA GEIGY AG (CH) | 1994-01-26 | — | — | EP | disclosed |
| US-5130429-A | Methylation with formaldehyde in a solvent and distillation | CIBA-GEIGY CORPORATION (US) | 1992-07-14 | — | — | US | disclosed |
| EP-0319480-A2 | Process for the methylation of triazine compounds containing 2,2,6,6-tetramethylpiperidine groups | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |