Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369451 | 0.87 | KMT2A (0.47) | KMT2ALMNAGAAPKM | |
| SCHEMBL27698517 | 0.79 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4KMT2ANPC1 | |
| SCHEMBL16398010 | 0.79 | SLC6A2 (0.46) | SLC6A2SLC6A3SLC6A4KMT2A | |
| SCHEMBL15918554 | 0.74 | MRGPRX4 (0.44) | — | |
| SCHEMBL27698516 | 0.74 | ESRRA (0.53) | SLC6A2SLC6A3SLC6A4KMT2ARAB9A | |
| SCHEMBL30313283 | 0.73 | CA9 (0.57) | POLBKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1957640 | 0.73 | CA9 (0.57) | POLBKMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL716550 | 0.72 | GAA (0.54) | POLBKMT2ARAB9ALMNAGAA | |
| SCHEMBL29443043 | 0.72 | GAA (0.54) | POLBKMT2ARAB9ALMNAGAA | |
| SCHEMBL9656925 | 0.72 | CREBBP (0.43) | SLC6A2SLC6A3SLC6A4POLBESRRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365915-B1 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| US-4956370-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| EP-0365915-A2 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1990-05-02 | — | — | EP | disclosed |