Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KRAS | P01116 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30313283 | 1.00 | CA9 (0.57) | CA9CA12CA1CA2CA7 | |
| SCHEMBL27877492 | 0.86 | CA12 (0.59) | CA9CA12CA1CA2CA7 | |
| SCHEMBL598460 | 0.86 | CA9 (0.68) | CA9CA12CA1CA2CA7 | |
| SCHEMBL184045 | 0.85 | CA12 (0.74) | CA9CA12CA1CA2CA7 | |
| SCHEMBL30822596 | 0.85 | CA12 (0.74) | CA9CA12CA1CA2CA7 | |
| SCHEMBL3116291 | 0.83 | KMT2A (0.58) | CA9CA12CA1CA2CA7 | |
| SCHEMBL5597547 | 0.83 | CA12 (0.71) | CA9CA12CA1CA2CA7 | |
| SCHEMBL13717859 | 0.83 | KMT2A (0.57) | KMT2ACES2CES1RAB9APOLB | |
| SCHEMBL9713357 | 0.83 | CA12 (0.55) | CA9CA12CA1CA2CA7 | |
| SCHEMBL18713981 | 0.83 | KMT2A (0.58) | CA9CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | FUJIFILM CORPORATION (JP) | 2025-10-23 | — | — | US | disclosed |
| US-20250092009-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2025-03-20 | — | — | US | disclosed |
| CN-111574510-B | Pyrimidine as herbicide Oxyphenyl derivatives | FMC 公司 | 2025-03-07 | — | — | CN | disclosed |
| EP-3094631-B2 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2024-12-25 | — | — | EP | disclosed |
| WO-2024043334-A1 | NOVEL PIPERAZINE DERIVATIVE OR SALT THEREOF AND PHARMACEUTICAL COMPOSITION | 富士フイルム株式会社 | 2024-02-29 | — | — | WO | disclosed |
| EP-3793988-B1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-11-15 | — | — | EP | disclosed |
| EP-3793988-B1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-11-15 | — | — | EP | disclosed |
| US-20230227423-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-07-20 | — | — | US | disclosed |
| US-20230227423-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-07-20 | — | — | US | disclosed |
| US-20230227423-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | CTXT PTY LTD (AU) | 2023-07-20 | — | — | US | disclosed |
| WO-2006077424-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2006-07-27 | — | — | WO | disclosed |
| WO-2005012256-A1 | 3, 4-DISUBSTITUTED 1H-PYRAZOLE COMPOUNDS AND THEIR USE AS CYCLIN DEPENDENT KINASES (CDK) AND GLYCOGEN SYNTHASE KINASE-3 (GSK-3) MODULATORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |
| US-20040029904-A1 | Spiro(2H-1benzopyran-2,4'-piperidine) derivates as glycine transport inhibitors | MERCK SHARP & DOHME B.V. (NL) | 2004-02-12 | — | — | US | disclosed |
| US-6645973-B1 | Heterocyclic amines such as 1-carboxymethyl-4-(4-chlorophenyl) spiro(2H-1-benzopyran-2,4'-piperidine)hydrochloride used for therapy of nervous system disorders; Alzheimer's, Parkinson's and Huntington's disease | AKZO NOBEL (NL) | 2003-11-11 | — | — | US | disclosed |
| EP-1232160-A1 | SPIRO(2H-1-BENZOPYRAN-2,4'-PIPERIDINE)DERIVATES AS GLYCINE TRANSPORT INHIBITORS | Akzo Nobel N.V. (NL) | 2002-08-21 | — | — | EP | disclosed |
| WO-2001036423-A1 | SPIRO(2H-1-BENZOPYRAN-2,4'-PIPERIDINE) DERIVATES AS GLYCINE TRANSPORT INHIBITORS | AKZO NOBEL N.V. (NL) | 2001-05-25 | — | — | WO | disclosed |
| US-5399584-A | Preventing gastrointestinal damage caused by nonsteroidal antiinflammatory drugs | THE PROCTER & GAMBLE COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0224332-B1 | HETEROCYCLIC AMINO COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1990-08-08 | — | — | EP | disclosed |
| US-4769367-A | ANTIDEPRESSANTS | GLAXO GROUP LIMITED (GB) | 1988-09-06 | — | — | US | disclosed |
| EP-0224332-A1 | Heterocyclic amino compounds | GLAXO GROUP LIMITED (GB) | 1987-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227423-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | STING1, CGAS, IRF3 | CA9 1629/4885CA12 743/4885CA1 1069/4885 |
| US-20250326744-A1 | PIPERAZINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION | ABCB11, ABCC1, SLC11A2 | CA9 2891/4885CA12 4365/4885CA1 4516/4885 |
| US-20040029904-A1 | Spiro(2H-1benzopyran-2,4'-piperidine) derivates as glycine transport inhibitors | SLC6A7, SLC1A2, SLC6A1 | CA9 3033/4885CA12 3936/4885CA1 2642/4885 |
| US-20250092009-A1 | SUBSTITUTED CONDENSED THIOPHENES AS MODULATORS OF STING | STING1, CGAS, IRF3 | CA9 1629/4885CA12 743/4885CA1 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.