Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1056933 | 1.00 | PRKD1 (0.68) | PRKD1 | |
| SCHEMBL6922426 | 0.91 | PRKD1 (0.82) | PRKD1 | |
| SCHEMBL6924025 | 0.90 | PRKD1 (0.55) | PRKD1 | |
| SCHEMBL6922259 | 0.88 | PRKD1 (0.84) | PRKD1 | |
| SCHEMBL936126 | 0.88 | PRKD1 (0.81) | PRKD1 | |
| SCHEMBL1059135 | 0.87 | PRKD1 (0.73) | PRKD1 | |
| SCHEMBL6922942 | 0.87 | PRKD1 (0.72) | PRKD1 | |
| SCHEMBL936340 | 0.86 | PRKD1 (0.83) | PRKD1 | |
| SCHEMBL6924016 | 0.86 | PRKD1 (0.67) | PRKD1 | |
| SCHEMBL6924033 | 0.85 | PRKD1 (0.64) | PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009484-A1 | ARYLPYRAZOLES AND ARYLISOXAZOLES AND THEIR USE AS PKD MODULATORS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | disclosed |
| WO-2011009484-A1 | ARYLPYRAZOLES AND ARYLISOXAZOLES AND THEIR USE AS PKD MODULATORS | NOVARTIS AG (CH) | 2011-01-27 | — | — | WO | disclosed |