Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.68 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31572500 | 0.87 | AOC3 (0.59) | TSHRMAPK1KMT2APPARGAOC3 | |
| SCHEMBL22785970 | 0.85 | AOC3 (0.54) | MAOBPPARGAOC3 | |
| SCHEMBL4822571 | 0.84 | MAOB (0.68) | MAOBMRGPRX4APPTSHRMAPK1 | |
| SCHEMBL9369893 | 0.83 | TSHR (0.57) | TSHRMAPK1PPARGAOC3 | |
| SCHEMBL791569 | 0.83 | MAOB (1.00) | MAOBMRGPRX4APPBCHE | |
| SCHEMBL9367809 | 0.83 | MAOB (0.62) | MAOBMRGPRX4APPTSHRMAPK1 | |
| SCHEMBL20816018 | 0.82 | KMT2A (0.57) | MAOBTSHRMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL4596162 | 0.82 | KMT2A (0.57) | MAOBTSHRMAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL9366692 | 0.81 | MAPK1 (0.53) | TSHRMAPK1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9188249 | 0.80 | KMT2A (0.58) | MAOBTSHRMAPK1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0391624-B1 | Substituted 1-[3-heteroarylmethoxy)phenyl] alkanols and related compounds in the treatment of asthma, arthritis and related diseases | PFIZER (US) | 1994-04-06 | — | — | EP | disclosed |
| US-5248685-A | Substituted 1-[3-(heteroarylmethoxy)phenyl]alkanols and related compounds in the treatment of asthma | PFIZER INC. (US) | 1993-09-28 | — | — | US | disclosed |
| WO-1990012006-A1 | SUBSTITUTED 1-[3-(HETEROARYLMETHOXY)PHENYL]ALKANOLS AND RELATED COMPOUNDS IN THE TREATMENT OF ASTHMA, ARTHRITIS AND RELATED DISEASES | PFIZER INC. (US) | 1990-10-18 | — | — | WO | disclosed |
| EP-0391624-A1 | Substituted 1-[3-heteroarylmethoxy)phenyl] alkanols and related compounds in the treatment of asthma, arthritis and related diseases | PFIZER INC. (US) | 1990-10-10 | — | — | EP | disclosed |