Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881518 | 0.87 | AR (0.42) | SLC6A2SLC6A3SLC6A4ARSLC22A12 | |
| SCHEMBL22904596 | 0.86 | SLC6A2 (0.47) | SLC6A2SLC6A3SLC6A4ARSLC22A12 | |
| SCHEMBL17085521 | 0.82 | KDM4E (0.41) | SLC6A2SLC6A3SLC6A4ARTAS1R3 | |
| SCHEMBL7015699 | 0.81 | AR (0.36) | SLC6A2SLC6A3SLC6A4ARSLC22A12 | |
| SCHEMBL22904395 | 0.79 | RHEB (0.44) | SLC6A2SLC6A3SLC6A4SLC22A12MEN1 | |
| SCHEMBL22904601 | 0.78 | VEGFA (0.51) | SLC6A2SLC6A3SLC6A4ARSLC22A12 | |
| SCHEMBL1154876 | 0.77 | SLC6A4 (0.50) | SLC6A2SLC6A3SLC6A4ARSLC22A12 | |
| SCHEMBL2127151 | 0.76 | CYP1A2 (0.44) | SLC6A2SLC6A3SLC6A4ARMEN1 | |
| SCHEMBL11755731 | 0.75 | SLC6A3 (0.49) | SLC6A2SLC6A3SLC6A4AREZH2 | |
| SCHEMBL22769777 | 0.74 | MAPK14 (0.46) | P2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365915-B1 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| US-4956370-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |