Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.57 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.57 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367695 | 1.00 | AGTR1 (0.57) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9367702 | 1.00 | AGTR1 (0.57) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9367461 | 0.92 | AGTR1 (0.60) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9367466 | 0.92 | AGTR1 (0.60) | AGTR1ABCC3ABCC2 | |
| SCHEMBL9367457 | 0.92 | AGTR1 (0.60) | AGTR1ABCC3ABCC2 | |
| SCHEMBL7054525 | 0.91 | AGTR1 (0.55) | AGTR1ABCC3ABCC2 | |
| SCHEMBL7054518 | 0.91 | AGTR1 (0.55) | AGTR1ABCC3ABCC2 | |
| SCHEMBL7054534 | 0.91 | AGTR1 (0.55) | AGTR1ABCC3ABCC2 | |
| SCHEMBL7052541 | 0.91 | AGTR1 (0.71) | AGTR1ABCC3ABCC2 | |
| SCHEMBL7052549 | 0.91 | AGTR1 (0.71) | AGTR1ABCC3ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425211-B1 | Substituted 5-((tetrazolyl)alkenyl)-imidazoles | SMITHKLINE BEECHAM CORP (US) | 1994-03-30 | — | — | EP | disclosed |
| US-5177096-A | Angiotensin II receptor antagonist | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-05 | — | — | US | disclosed |
| EP-0425211-A1 | Substituted 5-((tetrazolyl)alkenyl)-imidazoles | SMITHKLINE BEECHAM CORPORATION (US) | 1991-05-02 | — | — | EP | disclosed |