Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782175 | 0.92 | KMT2A (0.54) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL9845133 | 0.90 | KMT2A (0.52) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL9367677 | 0.87 | KMT2A (0.49) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL29149631 | 0.87 | PLAU (0.50) | KMT2AMEN1PARP10ALDH1A1PLAU | |
| SCHEMBL9706059 | 0.86 | MEN1 (0.49) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL9572453 | 0.79 | MEN1 (0.53) | KMT2AMEN1ALDH1A1PLAU | |
| Carbamic Acid SCHEMBL9362680 | 0.78 | KMT2A (0.57) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL27668608 | 0.76 | NPC1 (0.44) | PLAUPOLBTP53MAPT | |
| SCHEMBL27668609 | 0.75 | POLB (0.39) | KMT2AHTTALDH1A1POLBMAPT | |
| SCHEMBL697595 | 0.74 | KMT2A (0.60) | KMT2AMEN1HTTGFERHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409119-B1 | N,N'-Bis(alkoxy-alkyl)-pyridine-2,4-dicarboxylic acid amides, process for their preparation as well as their use | HOECHST AG (DE) | 1994-04-13 | — | — | EP | disclosed |