Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782175 | 0.94 | KMT2A (0.54) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL9845133 | 0.88 | KMT2A (0.52) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL9367677 | 0.88 | KMT2A (0.49) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL9367697 | 0.86 | KMT2A (0.50) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL9568958 | 0.84 | AAK1 (0.38) | MEN1KMT2AHSD17B10ACACBALDH1A1 | |
| SCHEMBL9573013 | 0.80 | KDM4E (0.36) | HSD17B10ACACBALDH1A1LMNAHPGD | |
| SCHEMBL9662430 | 0.78 | LMNA (0.36) | HTTKMT2AHSD17B10ALDH1A1POLB | |
| SCHEMBL19664384 | 0.77 | KMT2A (0.45) | MEN1KMT2AALDH1A1POLBJMJD6 | |
| SCHEMBL9663046 | 0.76 | TSHR (0.38) | KMT2AACACBLMNATSHR | |
| SCHEMBL7871639 | 0.76 | AAK1 (0.35) | KMT2AHSD17B10ACACBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479177-A2 | 4- or 5-substituted pyridine-2-carboxylic acids, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-04-08 | — | — | EP | disclosed |