Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 11/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367743 | 1.00 | IDO1 (0.40) | IDO1CYP2C9LMNACYP1A2CYP3A4 | |
| SCHEMBL9366353 | 0.83 | CYP19A1 (0.45) | IDO1CYP2C9LMNACYP1A2CYP3A4 | |
| SCHEMBL9366348 | 0.83 | CYP19A1 (0.45) | IDO1CYP2C9LMNACYP1A2CYP3A4 | |
| SCHEMBL9363361 | 0.82 | LMNA (0.41) | IDO1CYP2C9LMNACYP1A2CYP3A4 | |
| SCHEMBL9362738 | 0.79 | IDO1 (0.65) | IDO1CYP2C9LMNACYP1A2CYP3A4 | |
| SCHEMBL9821450 | 0.79 | IDO1 (0.65) | IDO1CYP2C9LMNACYP1A2CYP3A4 | |
| SCHEMBL9363001 | 0.79 | IDO1 (0.65) | IDO1CYP2C9LMNACYP1A2CYP3A4 | |
| SCHEMBL9821457 | 0.79 | IDO1 (0.65) | IDO1CYP2C9LMNACYP1A2CYP3A4 | |
| SCHEMBL3762407 | 0.79 | IDO1 (0.65) | IDO1CYP2C9LMNACYP1A2CYP3A4 | |
| SCHEMBL9362735 | 0.79 | IDO1 (0.65) | IDO1CYP2C9LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427242-B1 | Azole derivatives and antifungal drugs containing the same as an active component | KAO CORP (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5183824-A | Azole derivatives and antifungal drugs containing the same as an active component | KAO CORPORATION (JP) | 1993-02-02 | — | — | US | disclosed |
| US-5110826-A | AZOLE DERIVATIVES AND ANTIFUNGAL DRUGS CONTAINING THE SAME AS AN ACTIVE COMPONENT | KAO CORPORATION (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0427242-A1 | Azole derivatives and antifungal drugs containing the same as an active component | KAO CORPORATION (JP) | 1991-05-15 | — | — | EP | disclosed |