Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 3/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14416037 | 0.86 | QPCT (0.59) | QPCTCYP19A1HMOX1TBXAS1 | |
| SCHEMBL7875213 | 0.83 | KDM4E (0.61) | QPCTTBXAS1 | |
| SCHEMBL7868656 | 0.81 | CYP19A1 (0.57) | QPCTCYP19A1HMOX1TBXAS1 | |
| SCHEMBL7868470 | 0.80 | QPCT (0.59) | QPCTCYP19A1HMOX1TBXAS1 | |
| SCHEMBL19786259 | 0.80 | TBXAS1 (0.68) | QPCTTBXAS1 | |
| SCHEMBL3181153 | 0.79 | SMN1; SMN2 (0.57) | QPCTCYP19A1HMOX1TBXAS1 | |
| SCHEMBL28286843 | 0.79 | TBXAS1 (0.68) | QPCTTBXAS1 | |
| SCHEMBL13256613 | 0.79 | QPCT (0.65) | QPCTTBXAS1 | |
| SCHEMBL7879545 | 0.78 | SMN1; SMN2 (0.58) | QPCT | |
| SCHEMBL8445855 | 0.77 | QPCT (0.57) | QPCTCYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-A1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | Knoll AG (DE) | 1994-10-12 | — | — | EP | disclosed |