Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 13/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367046 | 1.00 | BRS3 (0.73) | BRS3PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL9366479 | 0.88 | BRS3 (0.77) | BRS3PTGS1PTGS2 | |
| SCHEMBL29565771 | 0.88 | BRS3 (0.77) | BRS3PTGS1PTGS2 | |
| SCHEMBL29406766 | 0.88 | BRS3 (0.77) | BRS3PTGS1PTGS2 | |
| SCHEMBL9367348 | 0.88 | BRS3 (0.77) | BRS3PTGS1PTGS2 | |
| SCHEMBL9367469 | 0.88 | BRS3 (0.77) | BRS3PTGS1PTGS2 | |
| SCHEMBL9367335 | 0.88 | BRS3 (0.77) | BRS3PTGS1PTGS2 | |
| SCHEMBL29478433 | 0.88 | BRS3 (0.77) | BRS3PTGS1PTGS2 | |
| SCHEMBL9370827 | 0.88 | BRS3 (0.77) | BRS3PTGS1PTGS2 | |
| SCHEMBL29566071 | 0.88 | BRS3 (0.77) | BRS3PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445039-B1 | Pyridylsulfonylurea and pyridylsulfonylthiourea derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1994-06-08 | — | — | EP | disclosed |
| EP-0445039-A1 | Pyridylsulfonylurea and pyridylsulfonylthiourea derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-09-04 | — | — | EP | disclosed |