Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 8/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 8/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514189 | 0.80 | ALDH1A1 (0.46) | LMNAALDH1A1CYP3A4CA12CA2 | |
| SCHEMBL19356939 | 0.76 | NR1H2 (0.42) | LMNAALDH1A1CYP3A4CA12CA2 | |
| SCHEMBL10978406 | 0.76 | SMN1; SMN2 (0.38) | LMNAALDH1A1HSD17B10MAPTTSHR | |
| SCHEMBL23931462 | 0.75 | ALDH1A1 (0.37) | LMNAALDH1A1CYP3A4CA12CA2 | |
| SCHEMBL6577199 | 0.72 | ALDH1A1 (0.46) | LMNAALDH1A1CYP3A4CA12CA2 | |
| SCHEMBL11529051 | 0.70 | MAPK1 (0.34) | CYP3A4TDP1 | |
| SCHEMBL7188832 | 0.69 | — | — | |
| SCHEMBL25118412 | 0.69 | TP53 (0.57) | HSD17B10MAPTMEN1RAB9AKMT2A | |
| SCHEMBL2239504 | 0.68 | CA12 (0.58) | LMNAALDH1A1CYP3A4CA12CA2 | |
| SCHEMBL31123642 | 0.68 | HSD17B10 (0.58) | LMNAALDH1A1CYP3A4CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365915-B1 | Substituted 2-aminothiazoles | BAYER AG (DE) | 1994-04-20 | — | — | EP | disclosed |
| US-4956370-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |