Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 15/20 | 0.45 |
| ▸ | RAB9A | P51151 | 15/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MECP2 | P51608 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371050 | 0.91 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL9367312 | 0.83 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL173683 | 0.83 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL18119249 | 0.82 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL14466539 | 0.80 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL391849 | 0.80 | ALDH1A1 (0.38) | SMN1; SMN2TSHRTP53HPGDKMT2A | |
| SCHEMBL21311966 | 0.79 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL14465412 | 0.77 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL502474 | 0.77 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL14466355 | 0.77 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332043-B1 | Oxadiazole derivatives containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them | HOECHST AG (DE) | 1994-05-18 | — | — | EP | disclosed |
| US-5216158-A | Oxadiazole compounds containing 4,6-bis-trichloromethyl-S-triazin-2-yl groups, process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-01 | — | — | US | disclosed |
| EP-0332043-A1 | Oxadiazole derivatives containing 4,6-bis-trichloromethyl-s-triazin-2-yl groups, process for their preparation and photosensitive mixture containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-09-13 | — | — | EP | disclosed |