Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ADA | P00813 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5301036 | 1.00 | TLR7 (0.40) | TLR7TLR8ALDH1A1POLBKMT2A | |
| SCHEMBL9368609 | 1.00 | TLR7 (0.40) | TLR7TLR8ALDH1A1POLBKMT2A | |
| SCHEMBL5283427 | 1.00 | TLR7 (0.40) | TLR7TLR8ALDH1A1POLBKMT2A | |
| SCHEMBL5297925 | 1.00 | TLR7 (0.40) | TLR7TLR8ALDH1A1POLBKMT2A | |
| SCHEMBL9444351 | 0.98 | TLR7 (0.39) | TLR7TLR8ALDH1A1POLBKMT2A | |
| SCHEMBL9700469 | 0.91 | MGLL (0.37) | TLR7 | |
| SCHEMBL9700482 | 0.91 | MGLL (0.37) | TLR7 | |
| SCHEMBL1962600 | 0.87 | TLR7 (0.38) | TLR7TLR8ALDH1A1POLBKMT2A | |
| SCHEMBL21494322 | 0.87 | TLR7 (0.38) | TLR7TLR8ALDH1A1POLBKMT2A | |
| SCHEMBL9408463 | 0.87 | TLR7 (0.38) | TLR7TLR8ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378910-B1 | Method for the preparation of imidazoles | TEXACO DEVELOPMENT CORP (US) | 1994-08-31 | — | — | EP | disclosed |
| EP-0378910-A1 | Method for the preparation of imidazoles | TEXACO DEVELOPMENT CORPORATION (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4921969-A | Method for the preparation of imidazoles | TEXACO CHEMICAL CO. (US) | 1990-05-01 | — | — | US | disclosed |