Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 3/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.45 |
| ▸ | CBR1 | P16152 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10637066 | 0.88 | TTR (0.52) | HSP90AA1HPGDTTRNR1I2LMNA | |
| SCHEMBL10636882 | 0.88 | TTR (0.52) | HSP90AA1HPGDTTRNR1I2LMNA | |
| SCHEMBL11689769 | 0.82 | TTR (0.57) | HSP90AA1HPGDTTRNR1I2LMNA | |
| SCHEMBL10641980 | 0.81 | TTR (0.47) | HSP90AA1HPGDTTRNR1I2LMNA | |
| SCHEMBL10640830 | 0.81 | TTR (0.45) | HSP90AA1HPGDTTRNR1I2LMNA | |
| SCHEMBL10642289 | 0.81 | LMNA (0.45) | HSP90AA1HPGDTTRNR1I2LMNA | |
| SCHEMBL8080242 | 0.77 | KMT2A (0.47) | HSP90AA1HPGDMAPK1TTRNR1I2 | |
| SCHEMBL10637074 | 0.77 | LMNA (0.49) | HSP90AA1HPGDMAPK1TTRNR1I2 | |
| SCHEMBL9371356 | 0.76 | HSP90AA1 (0.54) | HSP90AA1HPGDLMNAMAPTALDH1A1 | |
| SCHEMBL10640136 | 0.75 | TTR (0.49) | HSP90AA1HPGDTTRNR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373472-B1 | Substituted sulfonyl ureas | BASF AG (DE) | 1994-06-08 | — | — | EP | disclosed |
| US-5100459-A | Herbicides, plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1992-03-31 | — | — | US | disclosed |
| US-5032167-A | Herbicides | BASF (DE) | 1991-07-16 | — | — | US | disclosed |
| EP-0373472-A1 | Substituted sulfonyl ureas | BASF Aktiengesellschaft (DE) | 1990-06-20 | — | — | EP | disclosed |