Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372311 | 0.85 | SMN1; SMN2 (0.50) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL9368578 | 0.84 | RAB9A (0.57) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| Hydrochloric Acid SCHEMBL9368907 | 0.83 | RAB9A (0.56) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL9846281 | 0.80 | SMN1; SMN2 (0.44) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL9717917 | 0.77 | RAB9A (0.52) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL9368581 | 0.76 | RAB9A (0.57) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL9372321 | 0.76 | SMN1; SMN2 (0.59) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL9368175 | 0.76 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| Hydrochloric Acid SCHEMBL9373370 | 0.75 | RAB9A (0.56) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL9368584 | 0.74 | RAB9A (0.60) | RAB9ASMN1; SMN2TP53LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419210-B1 | Novel benzimidazole compounds and their use | PFIZER (US) | 1994-11-02 | — | — | EP | claimed |
| EP-0419210-A1 | Novel benzimidazole compounds and their use | PFIZER INC. (US) | 1991-03-27 | — | — | EP | claimed |
| EP-0419210-B1 | Novel benzimidazole compounds and their use | PFIZER (US) | 1994-11-02 | — | — | EP | disclosed |
| US-5141950-A | Enzyme inhibitors; treating asthma; antiarthritic agent | PFIZER INC. (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0419210-A1 | Novel benzimidazole compounds and their use | PFIZER INC. (US) | 1991-03-27 | — | — | EP | disclosed |