Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9369958 | 0.99 | CHRM2 (0.58) | CHRM2CHRM1EPHX2 | |
| SCHEMBL8871811 | 0.86 | CHRM2 (0.55) | CHRM2CHRM1EPHX2 | |
| SCHEMBL9370449 | 0.81 | CHRM2 (0.65) | CHRM2CHRM1 | |
| SCHEMBL8871375 | 0.80 | CHRM2 (0.67) | CHRM2CHRM1 | |
| SCHEMBL194766 | 0.75 | CHRM2 (1.00) | CHRM2CHRM1 | |
| SCHEMBL9370592 | 0.74 | CHRM2 (0.46) | CHRM2EPHX2 | |
| SCHEMBL17558315 | 0.74 | CHRM2 (0.43) | CHRM2EPHX2 | |
| SCHEMBL18983925 | 0.74 | CHRM2 (0.43) | CHRM2EPHX2 | |
| SCHEMBL661864 | 0.73 | CHRM2 (0.85) | CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL8871854 | 0.72 | CHRM2 (0.82) | CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239309-B1 | Oxadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME (GB) | 1994-01-12 | — | — | EP | claimed |
| EP-0239309-B1 | Oxadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME (GB) | 1994-01-12 | — | — | EP | disclosed |
| EP-0239309-A2 | Oxadiazoles useful in the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1987-09-30 | — | — | EP | disclosed |