Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | DGAT2 | Q96PD7 | 3/20 | 0.35 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17558298 | 0.79 | DGAT2 (0.45) | CHRM2DGAT2MGAT2EPHX2CPT2 | |
| SCHEMBL9369050 | 0.76 | CHRM2 (0.54) | CHRM2 | |
| SCHEMBL2593261 | 0.76 | CPT2 (0.48) | CHRM2DGAT2MGAT2EPHX2CPT2 | |
| SCHEMBL9369870 | 0.75 | CHRM2 (0.55) | CHRM2 | |
| SCHEMBL9369613 | 0.75 | CHRM2 (0.49) | CHRM2 | |
| SCHEMBL9368588 | 0.74 | CHRM2 (0.59) | CHRM2EPHX2 | |
| SCHEMBL9376174 | 0.74 | CHRM2 (0.43) | CHRM2EPHX2HSD11B1 | |
| SCHEMBL9372338 | 0.74 | CHRM2 (0.54) | CHRM2 | |
| Hydrochloric Acid SCHEMBL9372376 | 0.74 | CHRM2 (0.54) | CHRM2 | |
| Hydrochloric Acid SCHEMBL9369958 | 0.73 | CHRM2 (0.58) | CHRM2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307140-B1 | Oxadiazolyl-azabicycloheptanes for the treatment of senile dementia | MERCK SHARP & DOHME (GB) | 1994-03-02 | — | — | EP | disclosed |