Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.57 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 8/20 | 0.47 |
| ▸ | BRD2 | P25440 | 8/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 8/20 | 0.47 |
| ▸ | CCKBR | P32239 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9368798 | 1.00 | SENP1 (0.57) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL9368786 | 1.00 | SENP1 (0.57) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL8548014 | 0.87 | SENP1 (0.57) | SENP1CCKBR | |
| SCHEMBL9842511 | 0.86 | SENP1 (0.60) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL9842497 | 0.86 | SENP1 (0.60) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL9842505 | 0.86 | SENP1 (0.60) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL5657926 | 0.86 | SENP1 (0.75) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL9251712 | 0.82 | SENP1 (0.58) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL9251716 | 0.82 | SENP1 (0.58) | SENP1SCN9ABRD4BRD2BRD3 | |
| SCHEMBL9260046 | 0.82 | SENP1 (0.59) | SENP1SCN9ABRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0595980-A1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LTD. (GB) | 1994-05-11 | — | — | EP | disclosed |
| WO-1993002078-A1 | BENZODIAZEPINE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY | MERCK SHARP & DOHME LIMITED (GB) | 1993-02-04 | — | — | WO | disclosed |