Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369842 | 0.82 | MAPT (0.48) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL9373393 | 0.81 | KDM4E (0.47) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL23354874 | 0.77 | MAPT (0.47) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL4433469 | 0.76 | MEN1 (0.51) | MAPTKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL2229747 | 0.76 | NOTUM (0.66) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL9377228 | 0.75 | NOTUM (0.52) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL9375434 | 0.74 | NOTUM (0.49) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL18320914 | 0.74 | MAPT (0.60) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL4422155 | 0.74 | NOTUM (0.58) | MAPTKDM4EMEN1KMT2ALMNA | |
| SCHEMBL29873431 | 0.73 | MAPT (0.45) | MAPTKDM4EMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358595-B1 | N-hetaryl imidazole derivatives | SCHERING AG (DE) | 1994-05-11 | — | — | EP | claimed |
| EP-0518960-B1 | DERIVATIVES OF N-PHENYL GLYCINAMIDE, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | RHONE POULENC RORER SA (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0518960-A1 | DERIVATIVES OF N-PHENYL GLYCINAMIDE, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM. | RHONE POULENC RORER SA (FR) | 1992-12-23 | — | — | EP | disclosed |
| WO-1991013907-A1 | DERIVATIVES OF N-PHENYL GLYCINAMIDE, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1991-09-19 | — | — | WO | disclosed |
| US-4987146-A | N-hetaryl imidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |