Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9374689 | 0.82 | HSD17B10 (0.46) | MAPTALDH1A1LMNANPC1MAPK1 | |
| SCHEMBL9372444 | 0.81 | EGLN1 (0.53) | MAPTALDH1A1RAB9AKDM4ETDP1 | |
| SCHEMBL1192845 | 0.80 | ALDH1A1 (0.55) | MAPTALDH1A1LMNANPC1MAPK1 | |
| Hydrochloric Acid SCHEMBL1192843 | 0.79 | MAPT (0.54) | MAPTALDH1A1LMNANPC1MAPK1 | |
| SCHEMBL4422155 | 0.77 | NOTUM (0.58) | NOTUMMAPTALDH1A1LMNANPC1 | |
| SCHEMBL23441765 | 0.77 | KDM4E (0.51) | MAPTALDH1A1LMNANPC1RAB9A | |
| SCHEMBL4433469 | 0.76 | MEN1 (0.51) | NOTUMMAPTALDH1A1KDM4ETDP1 | |
| SCHEMBL2229747 | 0.76 | NOTUM (0.66) | NOTUMMAPTALDH1A1LMNANPC1 | |
| SCHEMBL1193289 | 0.74 | EGLN1 (0.68) | MAPTALDH1A1LMNANPC1MAPK1 | |
| SCHEMBL9368784 | 0.74 | MAPT (0.50) | NOTUMMAPTALDH1A1LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358595-B1 | N-hetaryl imidazole derivatives | SCHERING AG (DE) | 1994-05-11 | — | — | EP | claimed |
| US-4987146-A | N-hetaryl imidazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-22 | — | — | US | disclosed |