SCHEMBL9368807

SCHEMBL9368807

CCOC1CCCCN1OCC

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
THRB P10828 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11360985 0.98 ALDH1A1 (0.34) ALDH1A1THRBATML3MBTL1
SCHEMBL5559448 0.77 TSHR (0.30) L3MBTL1
SCHEMBL14215996 0.75 CYP1A2 (0.38) ALDH1A1THRBATML3MBTL1
SCHEMBL28870943 0.75 MEN1 (0.35) ALDH1A1
SCHEMBL28265108 0.74
SCHEMBL4635197 0.73 ALDH1A1 (0.33) ALDH1A1THRBATML3MBTL1
SCHEMBL28801681 0.73 ALDH1A1 (0.33) ALDH1A1THRBATML3MBTL1
Hydrochloric Acid SCHEMBL28297019 0.73 CYP1A2 (0.37) ALDH1A1THRBATML3MBTL1
SCHEMBL28284568 0.73 KMT2A (0.38) ALDH1A1
SCHEMBL28235216 0.71 POLB (0.37) ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2697232-A1 6,7 - DIHYDROIMIDAZO [2, 1 - B][1, 3]OXAZINE BACTERICIDES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2014-02-19 EP disclosed
CN-103596960-A 6, 7-dihydroimidazo [2,1-B ] [1,3] oxazine fungicides OTSUKA PHARMA CO LTD 2014-02-19 CN disclosed
WO-2012141338-A1 6,7 - DIHYDROIMIDAZO [2, 1 - B] [1, 3] OXAZINE BACTERICIDES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2012-10-18 WO disclosed
CN-102083812-A Muscarinic receptor agonits useful in the treatment of pain, alzheimer's disease and schizophrenia ASTRAZENECA AB 2011-06-01 CN disclosed
EP-0466586-B1 Disubstituted polymethylene-imines, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1994-09-28 EP disclosed
EP-0466586-A1 Disubstituted polymethylene-imines, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1992-01-15 EP disclosed
EP-0090733-B1 DISUBSTITUTED POLYMETHYLENE IMINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ADIR (FR) 1985-10-30 EP disclosed