Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873719 | 0.88 | CHRM2 (0.61) | CHRM2CHRM1 | |
| SCHEMBL9370169 | 0.81 | CHRM2 (0.55) | CHRM2CHRM1 | |
| SCHEMBL9375366 | 0.80 | CHRM2 (0.35) | CHRM2CHRM1 | |
| SCHEMBL10518263 | 0.78 | CHRM2 (0.36) | CHRM2CHRM1 | |
| SCHEMBL9370404 | 0.73 | CHRM2 (0.47) | CHRM2CHRM1 | |
| SCHEMBL661864 | 0.72 | CHRM2 (0.85) | CHRM2CHRM1 | |
| SCHEMBL194766 | 0.71 | CHRM2 (1.00) | CHRM2CHRM1 | |
| SCHEMBL9369870 | 0.71 | CHRM2 (0.55) | CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9372376 | 0.70 | CHRM2 (0.54) | CHRM2CHRM1 | |
| SCHEMBL9369050 | 0.70 | CHRM2 (0.54) | CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307140-B1 | Oxadiazolyl-azabicycloheptanes for the treatment of senile dementia | MERCK SHARP & DOHME (GB) | 1994-03-02 | — | — | EP | disclosed |
| EP-0307140-A1 | Oxadiazolyl-azabicycloheptanes for the treatment of senile dementia | MERCK SHARP & DOHME LTD. (GB) | 1989-03-15 | — | — | EP | disclosed |