SCHEMBL9375366

SCHEMBL9375366

CN(C)c1noc(C2CN3CC(=O)C2C3)n1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 2/20 0.35
CHRM1 P11229 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9368945 0.80 CHRM2 (0.55) CHRM2CHRM1
SCHEMBL9370169 0.77 CHRM2 (0.55) CHRM2CHRM1
SCHEMBL10518263 0.75 CHRM2 (0.36) CHRM2CHRM1
SCHEMBL9370106 0.72 CHRM2 (0.35) CHRM2CHRM1
Hydrochloric Acid SCHEMBL9724688 0.72 CHRM2 (0.65) CHRM2CHRM1
SCHEMBL9148287 0.71
SCHEMBL9369756 0.70 CHRM2 (0.33) CHRM2CHRM1
SCHEMBL9370120 0.70 CHRM2 (0.33) CHRM2CHRM1
SCHEMBL8873427 0.67 CHRM2 (0.61) CHRM2CHRM1
SCHEMBL9370251 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0307140-B1 Oxadiazolyl-azabicycloheptanes for the treatment of senile dementia MERCK SHARP & DOHME (GB) 1994-03-02 EP disclosed
EP-0307140-A1 Oxadiazolyl-azabicycloheptanes for the treatment of senile dementia MERCK SHARP & DOHME LTD. (GB) 1989-03-15 EP disclosed