Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538300 | 0.93 | FFAR1 (0.46) | OXER1FFAR1FFAR4MRGPRX4SRD5A1 | |
| SCHEMBL9538924 | 0.91 | OXER1 (0.46) | OXER1FFAR1MCL1FFAR4MRGPRX4 | |
| SCHEMBL9538976 | 0.90 | PPARD (0.41) | FFAR1MRGPRX4HTR6MAOBHTR1A | |
| SCHEMBL9541818 | 0.90 | MCL1 (0.42) | FFAR1MCL1MRGPRX4MAOBPTGER1 | |
| SCHEMBL9539906 | 0.88 | PTGER1 (0.46) | OXER1MCL1FFAR4MRGPRX4HTR6 | |
| SCHEMBL9369287 | 0.87 | FFAR1 (0.45) | OXER1FFAR1FFAR4MRGPRX4 | |
| SCHEMBL9376615 | 0.87 | MRGPRX4 (0.53) | OXER1FFAR1FFAR4MRGPRX4MAOB | |
| SCHEMBL9368734 | 0.86 | MCL1 (0.40) | OXER1FFAR1CYSLTR2CYSLTR1MCL1 | |
| SCHEMBL9369456 | 0.86 | OXER1 (0.49) | OXER1HTR6SRD5A1SRD5A2HTR1A | |
| SCHEMBL9369752 | 0.85 | OXER1 (0.47) | OXER1HTR6SRD5A1SRD5A2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600084-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |