Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9541818 | 0.94 | MCL1 (0.42) | PPARDPPARGPPARANR4A2MAOA | |
| SCHEMBL9369149 | 0.90 | OXER1 (0.45) | MAOBMRGPRX4HTR6HTR1AHTR1D | |
| SCHEMBL9538300 | 0.84 | FFAR1 (0.46) | MRGPRX4FFAR1 | |
| SCHEMBL9538924 | 0.81 | OXER1 (0.46) | PPARDPPARGPPARAMAOBMRGPRX4 | |
| SCHEMBL9153124 | 0.80 | PLA2G4A (0.38) | AKR1C3AKR1C2AKR1C4PTGS1HTR6 | |
| SCHEMBL9153111 | 0.79 | SRD5A1 (0.55) | AKR1C3AKR1C2AKR1C4PTGS1HTR6 | |
| SCHEMBL9539906 | 0.79 | PTGER1 (0.46) | MRGPRX4NPC1RAB9AHTR6HTR1A | |
| SCHEMBL9369131 | 0.78 | MRGPRX4 (0.53) | MRGPRX4NPC1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9369287 | 0.78 | FFAR1 (0.45) | MRGPRX4FFAR1 | |
| SCHEMBL9376615 | 0.77 | MRGPRX4 (0.53) | NR4A2MAOBMRGPRX4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |