Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9370556 | 0.99 | CHRM2 (0.67) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL8874183 | 0.91 | CHRM2 (0.59) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL8872958 | 0.74 | CHRM1 (0.50) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9459148 | 0.72 | KMT2A (0.41) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL7755561 | 0.69 | KMT2A (0.58) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9459105 | 0.68 | CHRM1 (0.44) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9458880 | 0.68 | KMT2A (0.40) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9458890 | 0.68 | CHRM2 (0.44) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9458909 | 0.68 | KMT2A (0.40) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL9342094 | 0.67 | CHRM1 (0.52) | CHRM2CHRM1CHRM4CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307140-B1 | Oxadiazolyl-azabicycloheptanes for the treatment of senile dementia | MERCK SHARP & DOHME (GB) | 1994-03-02 | — | — | EP | claimed |
| EP-0307140-B1 | Oxadiazolyl-azabicycloheptanes for the treatment of senile dementia | MERCK SHARP & DOHME (GB) | 1994-03-02 | — | — | EP | disclosed |