Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369295 | 0.88 | ALOX5 (0.82) | ALOX5 | |
| SCHEMBL9370427 | 0.86 | ALOX5 (0.65) | ALOX5 | |
| SCHEMBL9369626 | 0.86 | ALOX5 (0.65) | ALOX5 | |
| SCHEMBL9373164 | 0.84 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9369729 | 0.84 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9369330 | 0.83 | ALOX5 (0.61) | ALOX5 | |
| SCHEMBL9599442 | 0.81 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL9370176 | 0.81 | ALOX5 (0.67) | ALOX5 | |
| SCHEMBL9368836 | 0.80 | ALOX5 (0.69) | ALOX5 | |
| SCHEMBL9374469 | 0.80 | ALOX5 (0.81) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351194-B1 | Thiazole derivatives having a 5-lipoxygenase-inhibiting activity | ICI PLC (GB) | 1994-06-15 | — | — | EP | claimed |
| EP-0351194-A2 | Thiazole derivatives having a 5-lipoxygenase-inhibiting activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-17 | — | — | EP | claimed |
| EP-0351194-B1 | Thiazole derivatives having a 5-lipoxygenase-inhibiting activity | ICI PLC (GB) | 1994-06-15 | — | — | EP | disclosed |
| US-5196422-A | Antiinflammatory agents, antiallergens | ICI PHARMA (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5089513-A | Antiinflammatory agents; antiallergens; asthma; side effect reduction | ICI PHARMA (FR) | 1992-02-18 | — | — | US | disclosed |
| EP-0351194-A2 | Thiazole derivatives having a 5-lipoxygenase-inhibiting activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-17 | — | — | EP | disclosed |