Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | COMT | P21964 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9366597 | 0.83 | GAA (0.38) | GAAKDM4EBRD4ALDH1A1PKM | |
| SCHEMBL9370311 | 0.79 | COMT (0.38) | KDM4EALDH1A1COMTLMNASTAT3 | |
| SCHEMBL9367581 | 0.77 | COMT (0.37) | GAAKDM4EALDH1A1COMTLMNA | |
| SCHEMBL1686843 | 0.77 | COMT (0.41) | COMT | |
| SCHEMBL9367369 | 0.76 | COMT (0.36) | COMTLMNA | |
| SCHEMBL9366217 | 0.76 | COMT (0.36) | COMTLMNA | |
| SCHEMBL9367570 | 0.76 | COMT (0.40) | KDM4EALDH1A1COMTLMNATSHR | |
| SCHEMBL6181240 | 0.75 | COMT (0.40) | COMT | |
| SCHEMBL1686852 | 0.75 | COMT (0.40) | BRD4COMT | |
| SCHEMBL9371533 | 0.75 | COMT (0.40) | COMTLMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349340-B1 | Novel cephem compound, method for producing the same and anti-bacterial agent | MEIJI SEIKA CO (JP) | 1994-09-07 | — | — | EP | disclosed |
| US-4988686-A | Cephalosporin antibiotics | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0349340-A2 | Novel cephem compound, method for producing the same and anti-bacterial agent | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1990-01-03 | — | — | EP | disclosed |