Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COMT | P21964 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | OXTR | P30559 | 1/20 | 0.30 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1686852 | 0.83 | COMT (0.40) | COMT | |
| SCHEMBL9370311 | 0.82 | COMT (0.38) | COMTLMNATNF | |
| SCHEMBL9366201 | 0.81 | P2RX7 (0.32) | P2RX7HDAC4HDAC8 | |
| SCHEMBL1686711 | 0.81 | COMT (0.38) | COMTLMNAPDE10AOXTRTEAD4 | |
| SCHEMBL9367570 | 0.81 | COMT (0.40) | COMTLMNA | |
| SCHEMBL9367581 | 0.80 | COMT (0.37) | COMTLMNA | |
| SCHEMBL1686843 | 0.80 | COMT (0.41) | COMTTEAD4 | |
| SCHEMBL9366217 | 0.79 | COMT (0.36) | COMTLMNA | |
| SCHEMBL9366982 | 0.78 | COMT (0.38) | COMTTEAD4HDAC4HDAC8 | |
| SCHEMBL6181240 | 0.78 | COMT (0.40) | COMTTEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349340-B1 | Novel cephem compound, method for producing the same and anti-bacterial agent | MEIJI SEIKA CO (JP) | 1994-09-07 | — | — | EP | disclosed |
| US-4988686-A | Cephalosporin antibiotics | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-01-29 | — | — | US | disclosed |
| EP-0349340-A2 | Novel cephem compound, method for producing the same and anti-bacterial agent | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1990-01-03 | — | — | EP | disclosed |