Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MC4R | P32245 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | MC3R | P41968 | 1/20 | 0.48 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29102010 | 0.81 | KDM4E (0.53) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL7618500 | 0.78 | KDM4E (0.70) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL25894870 | 0.76 | BAZ2B (0.48) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL27497486 | 0.72 | KDM4E (0.68) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL7702024 | 0.72 | KDM4E (0.50) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL27791569 | 0.72 | KDM4E (0.55) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL29993937 | 0.70 | — | — | |
| SCHEMBL78340 | 0.70 | — | — | |
| SCHEMBL3186159 | 0.69 | KDM4E (0.70) | KDM4ENAPRTHCAR2ADORA3TSHR | |
| SCHEMBL29742199 | 0.69 | KDM4E (0.61) | KDM4ENAPRTHCAR2ADORA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322691-B1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-4895947-A | Process for producing 1-acyl-2-pyrazoline derivative | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0322691-A1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-07-05 | — | — | EP | disclosed |