Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 17/20 | 0.73 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7512284 | 0.91 | ADORA3 (0.69) | ADORA3ADORA1ADORA2A | |
| SCHEMBL29389782 | 0.91 | ADORA3 (0.83) | ADORA3ADORA1 | |
| SCHEMBL935050 | 0.91 | ADORA3 (0.83) | ADORA3ADORA1 | |
| SCHEMBL24615060 | 0.85 | ADORA3 (0.76) | ADORA3ADORA1 | |
| SCHEMBL19459489 | 0.83 | ADORA3 (0.82) | ADORA3ADORA1 | |
| SCHEMBL19520735 | 0.82 | ADORA3 (0.69) | ADORA3ADORA1 | |
| SCHEMBL6214808 | 0.82 | ADORA3 (0.89) | ADORA3ADORA1ADORA2A | |
| SCHEMBL6214803 | 0.82 | ADORA3 (0.89) | ADORA3ADORA1ADORA2A | |
| SCHEMBL6211242 | 0.82 | ADORA3 (0.86) | ADORA3ADORA1 | |
| SCHEMBL6211758 | 0.82 | ADORA3 (1.00) | ADORA3ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456419-B1 | A3 ADENOSINE RECEPTOR LIGANDS FOR MODULATION OF PIGMENTATION | ORADIN PHARMACEUTICAL LTD (IL) | 2016-11-23 | — | — | EP | disclosed |
| EP-2456419-A1 | A3 ADENOSINE RECEPTOR LIGANDS FOR MODULATION OF PIGMENTATION | Oradin Pharmaceutical Ltd. (IL) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011010306-A1 | A3 ADENOSINE RECEPTOR LIGANDS FOR MODULATION OF PIGMENTATION | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2011-01-27 | — | — | WO | disclosed |