Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370649 | 0.95 | ESR1 (0.50) | ESR1ESR2MAOBMAPK1CA12 | |
| SCHEMBL17595027 | 0.87 | ESR1 (0.56) | ESR1ESR2MAOBPTPN1GUSB | |
| SCHEMBL9376516 | 0.85 | CYP1A2 (0.51) | MEN1KMT2ACYP1A1CYP1A2CYP2E1 | |
| SCHEMBL22219101 | 0.84 | HSD17B1 (0.49) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL9373803 | 0.81 | MKNK1 (0.42) | MAPK1CA12CA1CA2CA7 | |
| SCHEMBL9376523 | 0.81 | DHODH (0.49) | MEN1KMT2ACYP1A1CYP1A2CYP2E1 | |
| SCHEMBL12049190 | 0.80 | CNR2 (0.46) | ESR1ESR2MAPK1CA12CA1 | |
| SCHEMBL21044559 | 0.78 | CA12 (0.50) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL9370132 | 0.78 | MCL1 (0.46) | MAPK1 | |
| SCHEMBL9370136 | 0.75 | MCL1 (0.52) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191451-B1 | 4-SUBSTITUTED PYRIDINE-2,6-DICARBOXYLIC ACID DERIVATIVES AND METHOD OF PREPARING SAME | OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) | 2019-06-05 | — | — | EP | claimed |
| EP-0341298-B1 | FLUORESCENT POLY(ARYLPYRIDINE) RARE EARTH CHELATES | BAXTER DIAGNOSTICS INC (US) | 1994-06-22 | — | — | EP | disclosed |
| US-5252740-A | Fluorescent poly(arylpyridine) rare earth chelates | BAXTER DIAGNOSTICS INC. (US) | 1993-10-12 | — | — | US | disclosed |
| US-5245038-A | Fluorescent poly(arylpyridine) rare earth chelates | BAXTER DIAGNOSTICS INC. (US) | 1993-09-14 | — | — | US | disclosed |
| US-5116989-A | Fluorescent poly(arylpyridine) rare earth chelates | BAXTER DIAGNOSTICS INC. (US) | 1992-05-26 | — | — | US | disclosed |
| US-5106957-A | Fluorescent poly(arylpyridine) rare earth chelates | BAXTER DIAGNOSTICS INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5055578-A | Fluorescent poly(arylpyridine) rare earth chelates | BAXTER DIAGNOSTICS INC. (US) | 1991-10-08 | — | — | US | disclosed |
| US-5032677-A | Fluorescent poly(arylpyridine) rare earth chelates | BAXTER INTERNATIONAL INC. (US) | 1991-07-16 | — | — | US | disclosed |
| EP-0341298-A4 | FLUORESCENT POLY(ARYLPYRIDINE) RARE EARTH CHELATES. | BAXTER INT (US) | 1990-02-20 | — | — | EP | disclosed |
| EP-0341298-A1 | FLUORESCENT POLY(ARYLPYRIDINE) RARE EARTH CHELATES | Baxter Diagnostics Inc. (US) | 1989-11-15 | — | — | EP | disclosed |
| WO-1989004826-A1 | FLUORESCENT POLY(ARYLPYRIDINE) RARE EARTH CHELATES | BAXTER INTERNATIONAL INC. (US) | 1989-06-01 | — | — | WO | disclosed |