Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371172 | 0.72 | MAPK1 (0.77) | MAPK1FNTAFNTBKDM4EALDH1A1 | |
| SCHEMBL3573417 | 0.72 | BACE1 (0.49) | BACE1ALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL6546743 | 0.71 | BACE1 (0.46) | MAPK1BACE1KDM4EALDH1A1HSD17B10 | |
| Dipyrocetyl SCHEMBL29508594 | 0.71 | MAPK1 (1.00) | MAPK1FNTAFNTBKDM4EALDH1A1 | |
| Dipyrocetyl SCHEMBL26164 | 0.71 | MAPK1 (1.00) | MAPK1FNTAFNTBKDM4EALDH1A1 | |
| SCHEMBL7993318 | 0.71 | BACE1 (0.51) | BACE1ALDH1A1TDP1HPGDPOLB | |
| SCHEMBL3557326 | 0.71 | BACE1 (0.48) | BACE1KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL5212814 | 0.70 | MAPK1 (0.71) | MAPK1FNTAFNTBKDM4EALDH1A1 | |
| SCHEMBL3939105 | 0.70 | MAPK1 (0.72) | MAPK1FNTAFNTBKDM4EALDH1A1 | |
| Dipyrocetyl SCHEMBL11121474 | 0.70 | MAPK1 (0.96) | MAPK1FNTAFNTBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589985-A1 | 2-AMINO-4-ARYL-THIAZOLES WITH ANTIASTHMATIC AND ANTI-INFLAMMATORY ACTIVITIES ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993000342-A1 | 2-AMINO-4-ARYL-THIAZOLES WITH ANTIASTHMATIC AND ANTI-INFLAMMATORY ACTIVITIES ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-01-07 | — | — | WO | disclosed |
| EP-0519449-A1 | 2-Amino-4-aryl thiazoles with antiasthmatic and antiinflammatory activities on the respiratory tract | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-12-23 | — | — | EP | disclosed |