Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367639 | 0.93 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9366847 | 0.91 | MAPT (0.47) | AGTR1AGTR2 | |
| SCHEMBL9370216 | 0.88 | CNR1 (0.43) | — | |
| SCHEMBL9366815 | 0.88 | MEN1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9366568 | 0.87 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9366410 | 0.87 | MALT1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9370771 | 0.86 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9366797 | 0.86 | AKR1C3 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9372220 | 0.85 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9371947 | 0.85 | AGTR1 (0.40) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411507-B1 | Pyrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-10-26 | — | — | EP | disclosed |
| US-5183899-A | Cardiovascular disorders, hypotensive disorders | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-02-02 | — | — | US | disclosed |
| EP-0411507-A1 | Pyrazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1991-02-06 | — | — | EP | disclosed |