Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21408470 | 0.98 | PIK3CD (0.48) | PIK3CDKMT2AMEN1PKMTSHR | |
| SCHEMBL1094551 | 0.90 | TSHR (0.46) | PIK3CDKMT2AMEN1PKMTSHR | |
| SCHEMBL9654604 | 0.90 | PIK3CD (0.47) | PIK3CDKMT2AMEN1PKMTSHR | |
| SCHEMBL1093605 | 0.90 | TSHR (0.46) | PIK3CDKMT2AMEN1PKMTSHR | |
| SCHEMBL23120127 | 0.89 | PIK3CD (0.46) | PIK3CDKMT2AMEN1PKMTSHR | |
| SCHEMBL11073870 | 0.88 | PIK3CD (0.48) | PIK3CDKMT2AMEN1PKMTSHR | |
| SCHEMBL11075549 | 0.87 | PIK3CD (0.47) | PIK3CDKMT2AMEN1PKMTSHR | |
| SCHEMBL10797384 | 0.86 | PIK3CD (0.50) | PIK3CDKMT2AMEN1PKMTSHR | |
| SCHEMBL9947409 | 0.86 | PIK3CD (0.43) | PIK3CDKMT2AMEN1PKMTSHR | |
| SCHEMBL261644 | 0.85 | PIK3CD (0.58) | PIK3CDKMT2AMEN1PKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462061-B1 | Triazole compounds useful as metal deactivators | CIBA GEIGY AG (CH) | 1994-08-10 | — | — | EP | disclosed |
| US-5298178-A | Benzotriazole derivative as metal deactivator | CIBA-GEIGY CORPORATION (US) | 1994-03-29 | — | — | US | disclosed |
| US-5133890-A | TRIAZOLE COMPOUNDS USEFUL AS METAL DEACTIVATORS | CIBA-GEIGY CORPORATION (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0462061-A1 | Triazole compounds useful as metal deactivators | CIBA-GEIGY AG (CH) | 1991-12-18 | — | — | EP | disclosed |
| US-4450102-A | AQUEOUS N-2-PYRROLIDONYL OR BIS/N-SUCCINIMIDYL/ALKYL SULFIDES OR DISULFIDES | PHILLIPS PETROLEUM COMPANY (US) | 1984-05-22 | — | — | US | disclosed |