Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370852 | 0.90 | PIK3CD (0.50) | PIK3CDKMT2AMEN1PKMBRD4 | |
| SCHEMBL21408470 | 0.88 | PIK3CD (0.48) | PIK3CDKMT2AMEN1PKMBRD4 | |
| SCHEMBL23120127 | 0.87 | PIK3CD (0.46) | PIK3CDKMT2AMEN1PKMBRD4 | |
| SCHEMBL11073870 | 0.87 | PIK3CD (0.48) | PIK3CDKMT2AMEN1PKMBRD4 | |
| SCHEMBL9056134 | 0.86 | ALOX5 (0.43) | PIK3CDKMT2AMEN1PKMBRD4 | |
| SCHEMBL463370 | 0.86 | ALOX5 (0.43) | PIK3CDKMT2AMEN1PKMBRD4 | |
| SCHEMBL10043 | 0.82 | — | — | |
| SCHEMBL1093605 | 0.81 | TSHR (0.46) | PIK3CDKMT2AMEN1PKMBRD4 | |
| SCHEMBL1094551 | 0.81 | TSHR (0.46) | PIK3CDKMT2AMEN1PKMBRD4 | |
| SCHEMBL9947409 | 0.81 | PIK3CD (0.43) | PIK3CDKMT2AMEN1PKMBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105130871-B | A kind of sulfur derivatives and its preparation method and application of pyrrolin ketone | 南京农业大学 | 2018-11-09 | — | — | CN | disclosed |
| EP-0241050-B1 | AZACYCLOALKANE DERIVATIVES, ABSORPTION PROMOTERS CONTAINING THE DERIVATIVES AS THE EFFECTIVE INGREDIENT AND EXTERNAL PREPARATION CONTAINING THE ABSORPTION PROMOTERS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-4882359-A | USED WITH DRUGS | HISAMITSU PHARMACEUTICAL CO., LTD. (JP) | 1989-11-21 | — | — | US | disclosed |
| WO-1987006226-A2 | AZACYCLOALKANE DERIVATIVES, ABSORPTION PROMOTERS CONTAINING THE DERIVATIVES AS THE EFFECTIVE INGREDIENT AND EXTERNAL PREPARATIONS CONTAINING THE ABSORPTION PROMOTERS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1987-10-22 | — | — | WO | disclosed |
| EP-0241050-A2 | Azacycloalkane derivatives, absorption promoters containing the derivatives as the effective ingredient and external preparation containing the absorption promoters | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 1987-10-14 | — | — | EP | disclosed |