Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3722353 | 0.86 | TSHR (0.47) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL7629696 | 0.86 | TSHR (0.56) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL17931228 | 0.78 | TSHR (0.45) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL28699769 | 0.77 | GAA (0.50) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL7629693 | 0.74 | TSHR (0.56) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL243559 | 0.74 | TSHR (0.70) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL17931090 | 0.73 | SCN1A (0.47) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL29022929 | 0.72 | KMT2A (0.49) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL17931321 | 0.72 | TSHR (0.40) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL17931234 | 0.71 | GAA (0.51) | TSHRKMT2AMAPTMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389422-B1 | Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions | CIBA GEIGY AG (CH) | 1994-09-21 | — | — | EP | disclosed |
| US-5015678-A | Light stabilized polymers by the addition of N-hydoxyamines | CIBA-GEIGY CORPORATION (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0389422-A2 | Stabilizers derived from N-hydroxy hindered amines by Michael addition reactions | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |