SCHEMBL9370937

SCHEMBL9370937

CC1CCN(CCCN2CCCCC2)C1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 9/20 0.48
SIGMAR1 Q99720 2/20 0.44
CARM1 Q86X55 1/20 0.42
PRMT6 Q96LA8 1/20 0.42
PRMT1 Q99873 1/20 0.42
PRMT8 Q9NR22 1/20 0.42
ACHE P22303 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4378122 0.90 HRH3 (0.54) HRH3SIGMAR1CARM1PRMT6PRMT1
SCHEMBL9374563 0.89 SIGMAR1 (0.46) HRH3SIGMAR1CARM1PRMT6PRMT1
SCHEMBL4375693 0.87 CARM1 (0.54) HRH3SIGMAR1CARM1PRMT6PRMT1
SCHEMBL9374424 0.85 HRH3 (0.53) HRH3
SCHEMBL12666 0.83 KDM4E (0.49) HRH3
SCHEMBL11907 0.83 KDM4E (0.49) HRH3
SCHEMBL15760641 0.83 SIGMAR1 (0.49) HRH3SIGMAR1CARM1PRMT6PRMT1
SCHEMBL4374854 0.83 CARM1 (0.54) HRH3SIGMAR1CARM1PRMT6PRMT1
SCHEMBL12449677 0.81 KDM4E (0.50) HRH3
SCHEMBL12942 0.81 KDM4E (0.50) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0415263-B1 Stabilisation of perfluorocarbon emulsions and perfluorinated heterocyclic compounds usable as emulsion stabilising additives KALI CHEMIE AG (DE) 1994-06-15 EP disclosed
US-5260496-A Process for separating mixtures of prefluorinated hydrocarbon compounds KALI-CHEMIE AG (DE) 1993-11-09 US disclosed
EP-0489773-B1 PROCESS FOR SEPARATING MIXTURES OF PARTIALLY FLUORINATED OR PERFLUORINATED HYDROCARBON COMPOUNDS KALI CHEMIE AG (DE) 1993-10-20 EP disclosed
EP-0489773-A1 PROCESS FOR SEPARATING MIXTURES OF PARTIALLY FLUORINATED OR PERFLUORINATED HYDROCARBON COMPOUNDS. KALI CHEMIE AG (DE) 1992-06-17 EP disclosed
US-5120731-A For use as oxygen carriers in blood substitutes KALIE-CHEMIE AG (DE) 1992-06-09 US disclosed
WO-1991003442-A2 PROCESS FOR SEPARATING MIXTURES OF PARTIALLY FLUORINATED OR PERFLUORINATED HYDROCARBON COMPOUNDS KALI-CHEMIE AKTIENGESELLSCHAFT (DE) 1991-03-21 WO disclosed
EP-0415263-A2 Stabilisation of perfluorocarbon emulsions and perfluorinated heterocyclic compounds usable as emulsion stabilising additives Kali-Chemie Aktiengesellschaft (DE) 1991-03-06 EP disclosed