Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | RARG | P13631 | 10/20 | 0.48 |
| ▸ | RARB | P10826 | 10/20 | 0.48 |
| ▸ | RARA | P10276 | 6/20 | 0.48 |
| ▸ | RXRA | P19793 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9371234 | 1.00 | ALDH1A1 (0.50) | ALDH1A1POLBGLATDP1L3MBTL1 | |
| SCHEMBL9537546 | 0.85 | UNG (0.45) | RARGRARBRARARXRALMNA | |
| SCHEMBL9370974 | 0.85 | UNG (0.45) | RARGRARBRARARXRALMNA | |
| SCHEMBL8114190 | 0.84 | NPC1 (0.51) | ALDH1A1POLBL3MBTL1RARBLMNA | |
| SCHEMBL8114187 | 0.84 | NPC1 (0.51) | ALDH1A1POLBL3MBTL1RARBLMNA | |
| SCHEMBL901112 | 0.83 | ALDH1A1 (0.68) | ALDH1A1POLBGLATDP1L3MBTL1 | |
| SCHEMBL901113 | 0.83 | ALDH1A1 (0.68) | ALDH1A1POLBGLATDP1L3MBTL1 | |
| SCHEMBL452233 | 0.83 | PTGS1 (0.60) | ALDH1A1RARBLMNANFKB1BLM | |
| SCHEMBL27959311 | 0.83 | PTGS1 (0.60) | ALDH1A1RARBLMNANFKB1BLM | |
| SCHEMBL9372704 | 0.82 | MAPT (0.47) | ALDH1A1TDP1L3MBTL1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600084-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |