Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 3/20 | 0.36 |
| ▸ | GLB1 | P16278 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370557 | 0.91 | ALDH1A1 (0.47) | ALDH1A1SLC6A2HPGDTACR2CA2 | |
| SCHEMBL20830104 | 0.91 | ALDH1A1 (0.47) | ALDH1A1SLC6A2HPGDTACR2CA2 | |
| SCHEMBL26207372 | 0.90 | ALDH1A1 (0.47) | ALDH1A1SLC6A2HPGDPDE4DTACR2 | |
| SCHEMBL14414818 | 0.85 | HPGD (0.53) | ALDH1A1SLC6A2HPGDTACR2MEN1 | |
| SCHEMBL21756599 | 0.85 | HPGD (0.53) | ALDH1A1SLC6A2HPGDTACR2MEN1 | |
| SCHEMBL14414850 | 0.85 | HPGD (0.53) | ALDH1A1SLC6A2HPGDTACR2MEN1 | |
| SCHEMBL5470533 | 0.85 | HPGD (0.53) | ALDH1A1SLC6A2HPGDTACR2MEN1 | |
| SCHEMBL5477125 | 0.85 | HPGD (0.53) | ALDH1A1SLC6A2HPGDTACR2MEN1 | |
| SCHEMBL10819414 | 0.85 | ALDH1A1 (0.60) | ALDH1A1HPGDTACR2GLB1CA2 | |
| SCHEMBL2623390 | 0.85 | ALDH1A1 (0.60) | ALDH1A1HPGDTACR2GLB1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394893-B1 | Purinyl and pyrimidinyl tetrahydrofurans | SQUIBB & SONS INC (US) | 1994-06-29 | — | — | EP | disclosed |
| US-5164520-A | Chemical intermediates for viricides | E. R. SQUIBB & SONS, INC. (US) | 1992-11-17 | — | — | US | disclosed |
| US-5145960-A | Viricides | E. R. SQUIBB & SONS, INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-5059690-A | Viricides | E. R. SQUIBB & SONS, INC. (US) | 1991-10-22 | — | — | US | disclosed |
| EP-0394893-A2 | Purinyl and pyrimidinyl tetrahydrofurans | E.R. SQUIBB & SONS, INC. (US) | 1990-10-31 | — | — | EP | disclosed |