Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 18/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9370270 | 0.90 | ALOX5 (0.67) | ALOX5 | |
| SCHEMBL9374357 | 0.84 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL7809281 | 0.84 | ALOX5 (0.63) | ALOX5 | |
| SCHEMBL9600434 | 0.83 | ALOX5 (0.79) | ALOX5 | |
| SCHEMBL9600447 | 0.83 | ALOX5 (0.79) | ALOX5 | |
| SCHEMBL10430937 | 0.82 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL9369696 | 0.81 | ALOX5 (0.52) | ALOX5 | |
| SCHEMBL9597849 | 0.77 | ALOX5 (0.57) | ALOX5 | |
| SCHEMBL9598075 | 0.77 | ALOX5 (0.62) | ALOX5 | |
| SCHEMBL9370176 | 0.75 | ALOX5 (0.67) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251299-B1 | Cephalosporin compounds, processes for their preparation and antibacterial agents | KAKEN PHARMA CO LTD (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0351194-B1 | Thiazole derivatives having a 5-lipoxygenase-inhibiting activity | ICI PLC (GB) | 1994-06-15 | — | — | EP | disclosed |
| US-5283245-A | Antiinflammatory agent, antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-02-01 | — | — | US | disclosed |
| US-5196422-A | Antiinflammatory agents, antiallergens | ICI PHARMA (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5089513-A | Antiinflammatory agents; antiallergens; asthma; side effect reduction | ICI PHARMA (FR) | 1992-02-18 | — | — | US | disclosed |
| US-5089495-A | Lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (FR) | 1992-02-18 | — | — | US | disclosed |
| EP-0381375-A1 | Heterocyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-08 | — | — | EP | disclosed |
| EP-0351194-A2 | Thiazole derivatives having a 5-lipoxygenase-inhibiting activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-17 | — | — | EP | disclosed |
| US-4822786-A | Cephalosporin compounds, and antibacterial agents | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |