Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.76 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084520 | 0.94 | MAOA (0.65) | MAOASIGMAR1HTR2ACYP2A6SMN1; SMN2 | |
| 4-Phenyl-Butylamine SCHEMBL132472 | 0.87 | MAOA (1.00) | MAOASIGMAR1HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL7337107 | 0.85 | MAOA (0.95) | MAOASIGMAR1HTR2ACYP2A6SMN1; SMN2 | |
| 4-Phenyl-Butylamine SCHEMBL8003688 | 0.85 | MAOA (0.95) | MAOASIGMAR1HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL12598856 | 0.85 | MAOA (0.95) | MAOASIGMAR1HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL23070514 | 0.85 | MAOA (0.95) | MAOASIGMAR1HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL3124979 | 0.85 | MAOA (0.95) | MAOASIGMAR1HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL7902062 | 0.85 | MAOA (0.95) | MAOASIGMAR1HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL8501696 | 0.85 | MAOA (0.95) | MAOASIGMAR1HTR2ACYP2A6SMN1; SMN2 | |
| SCHEMBL4869500 | 0.85 | MAOA (0.95) | MAOASIGMAR1HTR2ACYP2A6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591426-A1 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1994-04-13 | — | — | EP | disclosed |
| WO-1993000313-A2 | SIGMA RECEPTOR LIGANDS AND THE USE THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1993-01-07 | — | — | WO | disclosed |