Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 15/20 | 0.71 |
| ▸ | RAB9A | P51151 | 13/20 | 0.71 |
| ▸ | GAA | P10253 | 9/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 5/20 | 0.63 |
| ▸ | PKM | P14618 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372795 | 1.00 | NPC1 (0.71) | NPC1RAB9AGAAMAPTL3MBTL1 | |
| SCHEMBL9372789 | 1.00 | NPC1 (0.71) | NPC1RAB9AGAAMAPTL3MBTL1 | |
| SCHEMBL16418411 | 0.84 | NPC1 (0.64) | NPC1RAB9AGAAMAPTL3MBTL1 | |
| SCHEMBL9370161 | 0.81 | ALDH1A1 (0.60) | NPC1RAB9AGAAMAPTL3MBTL1 | |
| SCHEMBL9370149 | 0.81 | ALDH1A1 (0.60) | NPC1RAB9AGAAMAPTL3MBTL1 | |
| SCHEMBL9370153 | 0.81 | ALDH1A1 (0.60) | NPC1RAB9AGAAMAPTL3MBTL1 | |
| SCHEMBL15348115 | 0.78 | NPC1 (0.64) | NPC1RAB9AGAAMAPTL3MBTL1 | |
| SCHEMBL12767030 | 0.78 | NPC1 (0.64) | NPC1RAB9AGAAMAPTL3MBTL1 | |
| SCHEMBL28275739 | 0.78 | NPC1 (0.64) | NPC1RAB9AGAAMAPTL3MBTL1 | |
| SCHEMBL28260619 | 0.78 | NPC1 (0.64) | NPC1RAB9AGAAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322691-B1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS (JP) | 1994-06-15 | — | — | EP | claimed |
| US-4895947-A | Process for producing 1-acyl-2-pyrazoline derivative | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-01-23 | — | — | US | claimed |
| EP-0322691-A1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-07-05 | — | — | EP | claimed |
| EP-0322691-B1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-4895947-A | Process for producing 1-acyl-2-pyrazoline derivative | MITSUI TOATSU CHEMICALS, INC. (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0322691-A1 | Process for producing 1-acyl-2-pyrazoline derivatives | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-07-05 | — | — | EP | disclosed |