Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14621074 | 0.78 | — | — | |
| SCHEMBL12785478 | 0.76 | KDM4E (0.31) | TDP1 | |
| SCHEMBL24826189 | 0.76 | GRM4 (0.31) | — | |
| SCHEMBL10734060 | 0.63 | TDP1 (0.32) | TDP1 | |
| SCHEMBL1354859 | 0.61 | ABAT (0.31) | — | |
| SCHEMBL28683041 | 0.61 | — | — | |
| SCHEMBL30349713 | 0.60 | — | — | |
| SCHEMBL6032907 | 0.60 | ABAT (0.32) | TDP1 | |
| SCHEMBL27261830 | 0.59 | MAPT (0.33) | — | |
| SCHEMBL7932951 | 0.58 | PYGM (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354202-B1 | 2,6-Substituted 1,2- or 1,6-dihydropyridine compounds | MONSANTO CO (US) | 1994-09-14 | — | — | EP | disclosed |
| US-4908057-A | Substituted 2,6-substituted 1,2- or 1,6-dihydro pyridine compounds | MONSANTO COMPANY (US) | 1990-03-13 | — | — | US | disclosed |
| EP-0354202-A2 | 2,6-Substituted 1,2- or 1,6-dihydropyridine compounds | MONSANTO COMPANY (US) | 1990-02-07 | — | — | EP | disclosed |