Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193198 | 0.87 | CYP19A1 (0.53) | CYP19A1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL2141336 | 0.83 | CYP19A1 (0.56) | CYP19A1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL12203590 | 0.83 | CYP19A1 (0.56) | CYP19A1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL21816154 | 0.83 | CYP19A1 (0.56) | CYP19A1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL12945105 | 0.81 | CYP19A1 (0.42) | CYP19A1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL28928582 | 0.80 | CYP19A1 (0.53) | CYP19A1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL25391696 | 0.79 | ALDH1A1 (0.52) | CYP19A1ALDH1A1LMNAMEN1CASP3 | |
| SCHEMBL12945052 | 0.79 | CYP19A1 (0.51) | CYP19A1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL18925197 | 0.79 | CYP19A1 (0.55) | CYP19A1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL12945119 | 0.78 | CYP19A1 (0.51) | CYP19A1NPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011009934-A1 | TRIS(1,2,3-TRIAZOL-4-YL)METHANE ORGANOMETALLIC COMPOUNDS AS CATALYSTS AND PROCESSES USING THEM. | INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2011-01-27 | — | — | WO | disclosed |
| WO-2011009934-A1 | TRIS(1,2,3-TRIAZOL-4-YL)METHANE ORGANOMETALLIC COMPOUNDS AS CATALYSTS AND PROCESSES USING THEM. | INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2011-01-27 | — | — | WO | disclosed |